Quantitative magnetization transfer imaging using balanced SSFP

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Quantitative magnetization transfer imaging using balanced SSFP.

It is generally accepted that signal formation in balanced steady-state free precession (bSSFP) is a simple function of relaxation times and flip angle only. This can be confirmed for fluids, but for more complex substances, magnetization transfer (MT) can lead to a considerable loss of steady-state signal. Thus, especially in tissues, the analytical description of bSSFP requires a revision to ...

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Introduction. Magnetization transfer (MT) has become an important tool to study various tissue abnormalities, such as demyelination in brain white matter [1]. Recently, it has been shown that fast MT scans based on balanced steady-state free precession (bSSFP) with RF pulse modification achieve high SNR and high reproducibility at 1.5T [2]. At 3T, combination of multiple, phase-cycled, bSSFP sc...

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INTRODUCTION: Wideband SSFP (wbSSFP) is an alternating TR SSFP sequence that provides increased band spacing compared to conventional SSFP [1,2]. Like balanced SSFP (bSSFP), wbSSFP provides high signal-to noise efficiency and T2/T1 weighting. It has recently been shown that the signal intensity of bSSFP is strongly affected by magnetization transfer (MT) effects [3]. There has also been recent ...

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ژورنال

عنوان ژورنال: Magnetic Resonance in Medicine

سال: 2008

ISSN: 0740-3194,1522-2594

DOI: 10.1002/mrm.21705